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The primary outcome was the rate of aortic-root enlargement, expressed as the change in the maximum aortic-root-diameter z score indexed to body-surface area (hereafter, aortic-root z score) over a 3-year period In those Marfan syndrome patients who choose to become pregnant, close monitoring during pregnancy by both a high-risk obstetrician and a cardiologist familiar with Marfan syndrome is recommended
Marfan Syndrome is an inherited disorder of connective tissue, and is caused by genetic mutations that result in the dysregulation of the proteins of the extracellular matrix (fibrillin)
1%) occurred in the losartan group and 12 (18
Aortic dilatation, dissection and rupture are major concerns in the management of MFS patients
Aortic complications, such as
The 3-year rates of aortic-root surgery, aortic dissection, death, Atenolol vs
Marfan; aortopathy; racial/ethnic differences; treatment
Among individuals with Marfan syndrome, losartan failed to prevent aortic root or ascending aorta dilatation compared with atenolol
Aims: To determine the efficacy of losartan vs
Marfan syndrome is a condition you are born with that affect connective tissues
Rev Esp Cardiol (Engl Ed)