Airway obstruction and airway wall instability in cystic fibrosis: the isolated and combined effect of theophylline and sympathomimetics
The nurse is teaching the mother of a child with cystic fibrosis how to do postural drainage
Plasma protein binding for the majority of The pharmacokinetics of oral theophylline at steady-state were comparatively investigated in 13 asthmatic patients and in 10 patients with cystic fibrosis (CF)
Multiple aspects of lung function were measured in 17 cystic fibrosis (CF) patients on four occasions: without therapy (0); with oral theophylline medication (Th); after inhalation of salbutamol (beta 2); and with combined medication (Th + beta 2)
It has been observed previously that theophylline clearance is increased in patients with cystic
Dietary controls and
Hepatic impairment: Use with caution in patients with hepatic impairment (eg, cirrhosis, acute
Pharmacokinetics and bioavailability of oral theoph
Pharmacokinetics of theophylline and bioavailability of a sustained release theophylline preparation in patients with cystic
TheoCap Theophylline Anhydrous Uniphyl Dosage Forms Excipient information presented when available (limited, particularly for generics); consult specific
• Hepatic impairment: Use with caution in patients with hepatic impairment (eg, cirrhosis, acute hepatitis, cholestasis); risk of severe and potentially fatal theophylline toxicity is increased; theophylline clearance is • Intravenous aminophylline was administered to ten patients with cystic fibrosis (CF) to determine if the medication would improve pulmonary function and to study theophylline pharmacokinetics
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Theophylline is a bronchodilator with a low therapeutic index and a narrow therapeutic range (10-20 mcg/mL)
In people with liver problems, it can sometimes lead to a dangerous build-up of medication in the body
Dietary controls and logs were used to minimize the influence of food on theophylline metabolism
Study with Quizlet and memorize flashcards containing terms like A nurse is caring for a client with status asthmaticus
If theophylline is used in patients with CF, doses larger than those commonly given to asthmatics may be required to maintain therapeutic serum concentrations
Theophylline disposition (5
Peak theophylline samples were collected at 2 week intervals on four occasions in each asthmatic and on three occasions in each CF patient
ANS: D The symptoms described are the signs of theophylline toxicity
The care provider must be informed of this elevated serum level
Ann Allergy 1983; 50: 161–3
31-2
Sweat chloride test b
Clearance of the drug is increased in children (age 1 to 12), teenagers (12 to 16), adult smokers, elderly smokers, as well as in cystic fibrosis, and hyperthyroidism
The term ‘CF asthma’ refers to asthma-like symptoms and bronchial hyper-responsiveness in CF patients [2]