These include a buildup of lactic acid in the blood ( lactic acidosis ) and liver problems
612 mg L −1) <
info
Hepatotoxicity
05) with a mortality rate of 85% on exposure to 100 µg/L lamivudine in
3TC use during pregnancy has not been associated with adverse maternal, obstetric, or infant
Lamivudine is a prescription nucleoside reverse transcriptase inhibitor (NRTI) that is used in combination with other drugs as antiviral treatment for human immunodeficiency virus type-1 (HIV-1) and as a monotherapy for hepatitis B virus (HBV)
Introduction: A combination of zidovudine (AZT), lamivudine (3TC), and lopinavir/ritonavir (LPV/r) is one of the most effective drugs for preventing mother-to-child transmission (PMTCT) of HIV
Areas covered: We searched Pubmed to identify observational studies and randomized controlled trials reporting toxicity
Increased risk of hematologic toxicity
It is used for the treatment of HBV infection as a monotherapy and in combination with interferon
Drug information on Abacavir / Lamivudine for Patient
The results of the chronic toxicity tests showed that the tested concentrations of acyclovir, efavirenz and lamivudine caused a reduction in the fertility of females
Prolonged use of zidovudine has been associated with symptomatic myopathy
Lamivudine (Epivir-HBV) is usually taken once a day
Lamivudine is a dideoxynucleoside analogue which undergoes intracellular phosphorylation to the putative active metabolite, lamivudine triphosphate
This may be partly because lamivudine does not affect mitochondrial DNA synthesis
Apoptosis, or programmed cell death, is a tightly controlled
Genetic and reproductive toxicity of lamivudine, tenofovir disoproxil fumarate, efavirenz and their combination in the bone marrow and testicular cells of male mice February 2020 Annals of Science Lamivudine and zidovudine combination contains a fixed amount of each medicine
Lamivudine is a nucleoside analog that must be phosphorylated intracellularly to the active drug, lamivudine triphosphate (L-TP)
This activity reviews the indications, mechanism of action, and contraindications for zidovudine as a valuable agent in the treatment of HIV-1
Lamivudine is an antiretroviral drug that has