It may also be used to reduce swelling related to heart, kidney, or liver
Spironolactone is used to treat certain patients with hyperaldosteronism (the body produces too much aldosterone, a naturally occurring hormone); low
For edema: For oral dosage form (suspension): Adults—At first, 75 milligrams (mg) (15 milliliters [mL]) per day, taken in either single or divided doses
Spironolactone is used to treat fluid retention (oedema) caused by liver disease, kidney problems or heart failure
Spironolactone tablets are indicated as add-on therapy for the treatment of hypertension, to lower blood pressure in patients who are not
Background: Spironolactone, a non-selective mineralocorticoid receptor antagonist, can protect against cardiac fibrosis and left ventricular
Spironolactone antagonizes the effect of aldosterone and can lead to a reduction in fibrosis and an improvement in left ventricular (LV) function
1 Heart Failure
1 As the level of kidney function declines, the prevalence of hypertension increases and its treatment becomes more resistant to medications
Potassium and renal function were checked at weeks 1, 2, 4, 8, 16, 28 and 40
Why it is important to do this review The beneficial effects of spironolactone on diastolic function were not associated with any clinical improvement
Aldactone is used to treat heart failure, high blood pressure (hypertension), or hypokalemia ( low potassium levels in the blood)
Drug interactions, dosage, and pregnancy and breastfeeding information are provided
It's used to treat heart failure, high blood pressure, and swelling from kidney or liver problems in adults
Spironolactone has been shown to improve outcomes in patients with heart failure (HF) with reduced ejection fraction (EF)
1 Heart Failure
Heart failure (HF) is a complex set of clinical syndromes associated with abnormal heart structure or function that results in impaired ventricular ejection function or filling
Use as an add-on therapy for the treatment of hypertension, to lower blood pressure