sleepiness or unusual drowsiness
Jun 27, 2022 The American Psychiatry Association guidelines recommend that patients with treatment-resistant schizophrenia with an
We critically reviewed the literature on clozapine use in TRS, focusing on guidelines
Clozapine has been found to be an effective treatment
We identified the
Clozapine is said to be prescribed for around 37,000 Brits a year but can cause toxicity
You can find detailed information about this drug in the official Patient Information Leaflet (PIL)
Rash, fever, and swollen lymph nodes
5 Monitor the patient's troponin, CRP, and ECG at baseline, and 28 days into treatment
which include weight gain, hyperglycemia, seizures, tachycardia, myocarditis and neuromalignant syndrome , can affect the decision making process and even less severe side effects (sedation Clozapine can cause severe neutropenia (ANC <500/mm 3), Consider possibility of myocarditis or cardiomyopathy in patients with chest pain, dyspnea, persistent tachycardia at rest, palpitations, fever, flu-like symptoms, hypotension, or other manifestations of heart failure or ECG findings (e
Using Clozaril with other drugs that make you drowsy or slow your breathing can cause dangerous side effects or death
General Guidelines for Management of All Patients with Fever or with Neutropenia
This article provides a comprehensive guideline and checklist for clinicians who prescribe clozapine, covering the initiation, titration, maintenance, and discontinuation phases
In addition, clozapine is an effective treatment for schizophrenia accompanied by persistent suicidal or self-injurious behavior
1
Sinus tachycardia is a common adverse event associated with clozapine treatment
Thirty clozapine-treated patients with clinical tachycardia were investigated with 24-hour ambulatory electrocardiography (ECG)
Upon suspicion of these reactions, discontinue clozapine and obtain a cardiac evaluation