Levothyroxine ( l -thyroxine, l -T4) is a drug of choice for treating primary hypothyroidism, which in developing countries generally occurs due to Hashimoto
Ferrous gluconate can cause a decrease in the absorption of Levothyroxine resulting in a reduced serum concentration and potentially a
ferrous sulfate
Levothyroxine: Iron Preparations may decrease the serum concentration of Levothyroxine
Includes information on severity of interaction and the level of evidence
Aspirin reacts with ferrous gluconate in water at 0