Baclofen is an FDA-approved agonist of the gamma-aminobutyric acid (GABA) receptor, which is generally used for the relaxation of pathologic spasms
Baclofen, an agonist of the γ-aminobutyric acid B receptor, increases lower esophageal sphincter pressure and decreases swallowing rate
Conclusions: Baclofen was associated with a significant decrease in percent upright reflux by 24-h pH monitoring and a significant improvement in belching, regurgitation and overall symptom score
There is a small amount of evidence that suggests a medicine called baclofen might be useful
1%) have belching
When constant burping takes hold, anxiety could be the culprit
If you have excessive burping, it can be embarrassing, painful and cause anxiety
23, 24 Finally, central neuromodulators may be considered to help reduce psychological distress and raise symptom threshold (eg, bloating) that can trigger Belching can present in two different patterns, depending on the origin of the gas
However, computers may be wrong
We aimed to study the effect of baclofen in a placebo-controlled, double-blind, cross-over study in patients with clinically suspected rumination and/or SGB
Excessive burping can also cause other reflux symptoms, such as heartburn
Interestingly, baclofen also has a suppressive effect on swallowing rate that might contribute to improvement of aerophagia
Do not take more of it, do not take it more often, or do not take it longer than your doctor ordered
This meta-analysis is the first to pool clinical data from Background: Patients with aerophagia are believed to have excessive belches due to air swallowing
22, 23, 24 Currently, the only medication a doctor may prescribe to treat supragastric belching is baclofen, an antispasmodic and muscle relaxant
Pregnancy and Lactation Pregnancy